I have a lot of games to play now (Assassin's Creed 2, BioShock 2 and Darksiders) and on the way (Final Fantasy XIII, Yakuza 3, MLB '10 and GoW 3). After playing some Heavy Rain, I have decided to make this my "I can't sleep, I'll play this until I'm tired" game. I think this one will be best suited for playing in the middle of the night with its slower pace, frequent saves and midnight movie trappings. Eventually, I'll mix it up with some FFXIII. 
 
Boy, did Mr. Mars life go south or what?

I am not sure how long Heavy Rain is, but it seems like a game that could benefit from an all-nighter, taking origami breaks... :D
 
Have fun; avoid heavy machinery in the morning.

Well, I'm going to try for a Platinum so I figure I'll need plenty of replays. One guy (Shipwreck from Cheap Ass Gamers) said in his review that he amassed 28 trophies in 9 hours. I'll say it takes maybe 5 times that for all of them.
 
This is the closest thing to Shenmue I'll get to play, though you could say the same thing about Yakuza 3.

" Well, I'm going to try for a Platinum so I figure I'll need plenty of replays. One guy (Shipwreck from Cheap Ass Gamers) said in his review that he amassed 28 trophies in 9 hours. I'll say it takes maybe 5 times that for all of them.  This is the closest thing to Shenmue I'll get to play, though you could say the same thing about Yakuza 3. "

Its a short game anyway so dont worry about it interfering with your other games too much. I went from start to finish in one sitting.

"  One guy (Shipwreck from Cheap Ass Gamers) said in his review that he amassed 28 trophies in 9 hours."