I thought the slugs were implanted in the Little Sisters to assist their recycling ADAM from the dead of the civil war. You see the Little Sisters extracting blood from corpses and drinking it. Since they held such valuable cargo, the ADAM, Dr. Suchong created the Big Daddies to protect them as they went about their grisly work.
I don't think the slugs in the Little Sisters actually created the ADAM.
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