Bonsai

I don't think it's the absolute scariest, but a sound that always got me on edge was the sound of a regenerator breathing in RE4.

I.... I don't know if I can comprehend this...
 
CLEVER advertising for BulletStorm?  I think I need to go lie down...!

Uncharted 3 is number one on my list right now.

In this place called Giant Bomb
We do many things (but not your mom).
Mail packages that don't explode in ones face,
and kicking tanks into space. 
With quick looks and things,
like endurance runs and Bastion building.
All this at Giant Bomb.

Charlie made lots of envelopes 
And lots of models too.
Too bad there weren't more rainy days.
No meat dimension for you!

I would like to enter as well.

I honestly believe that game room still exists solely because Jeff buys the games every week.

 
I don't feel like finding a screenshot of it, but in the Double Dragon movie, you can see a Double Dragon arcade machine in the background in one point.
 
In the (terrible) movie Stay Alive, a character mentions Fatal Frame near the beginning.