I'm anticipating dissapointment, but the ones that will have me most dissapointed when what I hoped would be awesome turns out to not be are;
Tales of Symphonia: Dawn of the New World (not relesaed yet in PAL territories)
Resi V
Uncharted 2

And then there's the games from developers who never fail to impress,
Starcraft 2
Half-Life 2 Episode 3