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The protagonist of Prototype, Alex Mercer has been transformed by a virus into a shapeshifting weapon. He seeks to uncover the mysterious source of his abilities as well as fight the same virus as it consumes Manhattan.
The playable rogue in the original Diablo. By Diablo II, however, she has been corrupted by Andariel's power and serves as a boss in the second game.
The protagonist of the first Drakengard game and later returns as an antagonist in the sequel.
Chuck Greene is a former national motocross champion and the main male character of Dead Rising 2 and Dead Rising 2: Case Zero. He is the father of Katey Greene and must constantly acquire Zombrex for her.
Dante is the star of Capcom's Devil May Cry series and the son of the Legendary Dark Knight Sparda. He is also the owner of his own business as a demon hunter, stationed at his Devil May Cry shop along with Trish.
Eric Cartman is an animated character from the popular series 'South Park'. Eric Cartman appears in all current South Park games.
Ethan is a young 17 year old living aboard the Guardian's Colony within Gurhal when the SEED attacks. He joins the Guardian's as a Hunter and helps to defend the three planets from the SEED. Later on, he is involved within an assassination attempt against the Guardian president and becomes a fugitive.
Isaac is seventeen years old, and is the main character of Golden Sun. He trains under the Psynergy of earth, and is a Vale native.
JC Denton is the nano-augmented player controlled protagonist in the critically acclaimed first-person roleplaying game Deus Ex. Initially working for the United Nations Anti Terrorist Organization (UNATCO), JC's main job is to combat and stop terrorist organizations.
Jill Valentine is a former R.P.D. police officer and is now a member of the B.S.A.A. fighting Bio-Terrorism around the world. She is a staple of the series.
Tainted by his vampiric "gift," Kain rejects his duty as the scion of balance and chooses to lead an empire of vampires in the dying land of Nosgoth.
Lloyd Irving is the main protagonist of Tales of Symphonia. After being exiled from his village, he joins his friends on a lengthy journey to regenerate the world.
Known as Slick Clyde the vigilante in Vigilante 8 he became corrupted and soon became Lord Clyde the leader of the Coyotes in Vigilante 8 Second Offense.
A legendary basketball player who led the Chicago Bulls to six championships in eight years, plus a short stint with the Washington Wizards, before retiring for good in 2003. Jordan is currently the majority owner of the Charlotte Hornets.
Richter Belmont is the protagonist of Dracula X: Rondo of Blood and a central character in Symphony of the Night. He is the culmination of centuries of finely-honed vampire killing skills, yet falls prey to a curse that disgraces his family name for generations.
Sarah Kerrigan was a Terran Ghost before being captured by the Zerg on Tarsonis. After being Infested and transformed into a twisted Zerg hybrid, she came to rule the terrifying Swarm as the self-styled Queen of Blades.
Naruto's rival, but also closest friend. He's an integral character in the Naruto world. He is Itachi Uchiha's younger brother. He is also a former member of Team 7. After defeating Itachi, he loses Orochimaru's curse mark and is told the truth of the Uchiha's destruction and of Itachi's secret life by Tobi.
The Alchemist is a primarily spell-focused class in the PC/MAC action RPG Torchlight.
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