So according to this Easter Egg in Uncharted 3, Last of Us exists in the same universe.
http://www.youtube.com/watch?v=i8kiHEkiUcY&feature=youtube_gdata_player
So that means that Drake "saving the world" from the villains in the first 3 games was meaningless. Who knows, maybe those bad guys trying to harness the power of Shambala knew about the imminent fungal plague and were trying to stop it, but here comes asshole Nathan Drake and screws up their plan, dooming the world to the apocalypse.
Also I'm bummed that I sold my PS3 last year and can't play this. Discuss.
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