If anyone tries to make an innuendo, I'mma kill 'em. 
 
Anyways, I specced up Varric so that there would never be a chest that he couldn't unlock--something that plagued my playthroughs in origins. So, I got him up to 40 cunning, yet I only saw one master chest in my entire playthrough. I did most of the game's sidequests, despite some for companions I didn't really use. Anyone else felt slightly misguided?

Yo, Isabella's got a pretty boss chest. 
 

This is interesting to know because I was having that problem in this game during Act 1 and the beginning of Act 2.  I finally had gotten Isabella's cunning above 30.  But if there are only a few master chests, then I'm not sure I see enough reason to drop further points into cunning. 
 
And I had to really refrain myself from making an innuendo.  I doubt others will be so self-controlled.

I think I saw like two or three...

Like four of them and I wrote them down.

• In the Blooming Rose in one of the rooms upstairs
• At the Docks in the SW corner during nighttime
• In Hightown in a hidden path (not drawn on the map) in the SW corner during nighttime
• In the Hanged Man next to "A Friend" during nighttime (though I'm not entirely sure you have to have it set to nighttime) 

Really wish a mod for unlocking chests without a rogue would come out like DA:O so I can actually open them.

Is there anything ever, EVER in chests that's actually worth worry about? The most I every got was either junk or a piece of equipment that was worse then what I already have.

Think i saw a few, but I don't remember the loot being anything special.

I've done like 6. Nothing especially good in them. You get better loot by equipping shit that says it'll give you better loot, then killing dudes.

A few, nothing special in them.
Cunning is a stat I would say either coimpletely ignore or go full out on. A main character rogue can benefit greatly from cunning.

I've encountered, perhaps, 3-5 of them in my initial playthrough. 
 
One of particular note (lite-ish endgame spoilers) had me 'very' interested: 
 

What about traps?  Were there any traps in Act 3 that you needed over 30 cunning to disarm?  Cause if not, I'm not going to put anymore in Isabella's cunning.

Cunning adds defense also, its a kickass attribute.

"Like four of them and I wrote them down.

• In the Blooming Rose in one of the rooms upstairs
• At the Docks in the SW corner during nighttime
• In Hightown in a hidden path (not drawn on the map) in the SW corner during nighttime
• In the Hanged Man next to "A Friend" during nighttime (though I'm not entirely sure you have to have it set to nighttime) 

 And a few others that really weren't worth it, not that I'm saying these particular ones were worth it but they do hand you some experience "

I totally clicked on this thread thinking it said Master Chief.

I wasn't counting, but I would guess about a dozen or so.

" I totally clicked on this thread thinking it said Master Chief. "