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A young Asari highly skilled in both research and biotics, Liara T'Soni is one of Commander Shepard's companions in the Mass Effect series, as well as a potential love interest.
A master of biotics, Benezia is an extremely influential Asari Matriarch in league with Saren to find the Conduit.
A reconnaissance Reaper serving as a vanguard, attempting to summon an entire Reaper fleet to wipe out all organic life every fifty thousand years.
A female Quarian team member in the Mass Effect series. Tali is a capable engineer with highly developed technical skills. Throughout Mass Effect, Tali reveals much of the life of the Quarians. She is one of a select few characters fully playable throughout the Mass Effect Trilogy.
A human team member who accompanies Commander Shepard from the beginning of Mass Effect. Kaiden is skilled in both Biotics and Tech, but struggles to keep control, due to the physical side-effects of his implanting.
Former Captain of the Normandy and possibly the human representative on the Citadel council. He is voiced by the actor Keith David
Flight Lieutenant Jeff "Joker" Moreau is the pilot of both the SSV Normandy and the Normandy SR-2.
Admiral Steven Hackett is the commanding officer of the fifth fleet and an admiral in the Alliance Navy. During the events of Mass Effect, he gives Commander Shepard optional assignments related to the Systems Alliance. He is stationed at Arcturus Station.
Balak leads the terrorist group of Batarians in the first piece of downloadable content for Mass Effect, Bring Down the Sky. He despises humans, and attempts to crash Asteroid X57 into the human populated colony of Terra Nova.
Administrator Anoleis is a salarian who runs Port Hanshan on the planet of Noveria.
A side character in both Mass Effect 1 and 2 who implores Commander Shepard to assist her with undercover work.
A minor character that appears in the first Mass Effect, and may make a return in Mass Effect 2 dependent on a player choice. Voiced by Belinda Cornish.
Fai Dan is the leader of the colonists on Feros, and one of the few to avoid succumbing to the will of the Thorian.
The Rachni Queen is encountered first on Noveria, and Shepard's interaction with her determines the fate of her entire species.
Sparatus is a consistent thorn in Shepard's side throughout Mass Effect 1-3.
The turian head of Citadel Security, Executor Venari Pallin acts as the liaison between C-Sec and the Citadel Council. He has an office on the Presidium near the embassies. Unlike Garrus Vakarian, Pallin is extremely "by-the-book" in his work.
Chellick is a C-Sec detective on the Citadel and former colleague of Garrus Vakarian.
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