I personally am going for hardcore mode. I like games that make survival feel as real as possible. If you don't know hardcore modes makes you have to drink and eat to survive. Also ammo has weight and stimpacks take time to heal rather than just the instant heal. I also believe you cannot inject stimpacks into a single limb. So whats it gonna be?
 
EDIT: I was curious cause someone brought it up. Does hardcore mode just enable the survival stuff but you could still play on normal? If anyone knows please let me know =)

Well, I was planning on playing it the normal way the first time, and then hardcore during my 2nd playthrough, but uhh... I think I've changed my mind and am doing it in the opposite order. Hardcore first, normal second. 
 
Still, I'm worried that the hardcore mode won't further the game's level of immersion as much as I'd like, but regardless, I can't wait to play this game.

I enjoy the survival aspect of STALKER a whole lot. So Hardcore for me, whenever I decide to play it.

"Hardcore" usually means that, if you die, your character gets deleted and there's no way to restore it.  If "Hardcore" just means "Really hard and more realistic" and not "Your 50+ hour game is burned to dust because your video card got hung up on the waterfall animation", then I might be interested.

Normal,if theres a hardcore achieve ill prolly go back and get it

" Normal,if theres a hardcore achieve ill prolly go back and get it "

Hardcore, Fallout 3 was too easy on the hardest difficulty

" Hardcore, Fallout 3 was too easy on the hardest difficulty "

Well, Fallout 3 was my first real swim in the pool of role playing games(well, Mass Effect was, but that's a different animal if you ask me). So I'm not sure. Is there any information on how often you have to maintain yourself? And what exactly you have to do? Eat, sleep, toilet? lol

When I get around to playing the game, pretty sure I won't buy it at launch, I think I will play it on Hardcore, actually seems like it would be more fun that way.

I'll be starting on hardcore because it seems much more immersive, but I'll probably get extremely frustrated and start over on normal.

I'm excited to give harcore mode a shot - as others have said, for it's immersive potential.

Can't really tell if I'll stick with it or not until I play it and get a real sense of how brutal it is.

Think i will go Hardcore mode sounds internesting. Fallout 3 was pretty damn easy so a challenge would be good.

Normal then Hardcore.

Normal playthrough first then hardcore

Hardcore.
 
Because as invigorating as shoving ten stimpacks into my arm to restore my life instantly sounds...

Hardcore, I thought fallout 3 got way too easy about 6 hours in (maybe I should of turned up the difficulty slider but whatever)

" @Sackmanjones: Damn, was that an option in Fallout 3 also? because I was always hoping for something like that. "

Normal, I don't want to drive myself insane

I think I'll just go hardcore right from the get go. Don't wanna develop any bad habits.

Hardcore because I'm hardcore.

Well, it depends if food and drink is scarce or evenly spread throughout the game. If it was as scarce as purified water in Fallout 3, then it will be a real pain to have to go back in the middle of each quest to get a drink. If drinks can be found in reasonable amounts, then hardcore sounds fun!

Hardcore, cause I'm a weirdo survivalist. 

ill be starting the game on normal.

Probably Normal difficulty with Hardcore enabled.

Hardcore, and a kid killing mod of course

" @Sackmanjones: Damn, was that an option in Fallout 3 also? because I was always hoping for something like that. "

Hardcore sounds like a great idea but requires alot of input and effort, where as I just want to play the game. As the name suggests I reckon its best suited for the hardcore fans of the game.

Meh, the only thing I really used from the FWE mod was the 3X Global damage, which really made things more difficult in and of itself.  

" @Jasta:  I honstly think it would help anyone to get the full feel of the game. "

Hardcore 
 
I went through Fallout 3 on Very Hard, and still had to throw in my own restraints to make it more awesome. Like never using stimpacks so I would actually put the plumbing in the game to some use. I'm normal like that.

Hardcore sounds interesting, but I might pass at first.  I don't want to get bogged down with survival aspects of the game.  I'd rather enjoy just the "story" aspect of roleplaying. 
  
I did think that Fallout 3 was on the easier side, but I do enjoy the feeling of being a little too powerful and head shotting super mutants like a champ.

feel like the hardcore mode will only add frustration to the game, i mean, weighted ammo?! a bad idea, IMO. regardless, i will be playing this game on normal and it will be kick-ass!!

Not sure but I think hardcore. FO3 was pretty easy.

Normal.  The idea is interesting,  but I'll pass on that.

I usually go for the easiest mode the first time around. Just so I can check out the story without being frustrated. Then, if there's achievements or trophies for it,  I'll replay it on a harder difficulty.

Defenitely gonna play in hardcore mode. The survival experience in a Post apocolyptic world Just sounds great to me.( In game form please) And it is kinda logical Cus you know..  Post apocolyptic world.. 
And It makes me feel cool when im gonna brag about the stuff I did in hardcore mode:p

 
Normal.

I'll definitely play through it on hardcore at some point, but maybe not on my first character.  I'm not sure how the weighted ammo is going to play out...FO1 and FO2 had weighted ammo and it wasn't a problem, but the weapons in those games didn't degrade over time.  In Fallout 3 all the weight you saved in ammo was immediately taken up by carrying around extra weapons to repair your gear.

 I ended up playing the third Fallout 7 times so I'm pretty sure I'll be hitting up hardcore at least one of the times I play it.

normal to enjoy the story 
then hardcore just to see how bad i am at playing games :)

I think I'll probably start off with hardcore difficulty, and switch to normal if weighted ammo starts to annoy me.