During the story of Oblivion you must have a daedric item from one of the 14 available princes but over the course of your travels if you manage to lose, sell, give to the Adoring Fan so he cant move, etc Hermaeus Mora's quest becomes available. He tells you to collect a soul from every race in Tamriel. His daedric artifact is the Oghma Infinium a book which boosts your stats.
In the main quest for Skyrim you encounter a crazy hermit named Septimus Signus who is trying to gain enlightenment from opening a giant Dwemer safe, and after you succeed in helping him you are visited by Hermaeus Mora who tells you that you are to be his new champion. The daedric quest Discerning the Transmudane thus begins where Mora tells you to collect the blood of all the -mer or elven races. This includes Orsimer, Falmer, Altmer, Dunmer, and Bosmer. After you do so you return to Septimus and he opens the Dwemer box but is consumed by a flash of light. Sitting on a pedistal is the Oghma Infinium this time offering a plus 5 bonus to 3 different domains:
- The Path of Might- Archery, Heavy Armor, One-handed, Smithing, Two-handed, Block
- The Path of Shadow- Alchemy, Light Armor, Lockpicking, Pickpocket, Speech, Sneak
- The Path of Magic- Alteration, Conjuration, Destruction, Illusion, Restoration, Enchanting