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The corrupt male chief of police from Resident Evil 2.
Brian McBride is the Director of Operations for the CIA in Africa. He is a mysterious ally to Solid Snake and gives Snake vital information about the area via the codec system.
Founder and CEO of Aperture Science, Johnson is a constant overseer of Aperture tests by way of prerecorded voice messages.
Dana White is the current president of the UFC.
Manny Calavera's evil boss in Grim Fandango.
The Genetic Lifeform and Disk Operating System of the Aperture Science Enrichment Center in Portal. GLaDOS is a maniacal, rogue AI known for her disdain for humans and unintentionally humorous nature.
Ryan Chappelle is the Regional Director of CTU in '24: The Game'. A role he also played in three seasons of the popular television series '24'.
Prince of Los Angeles for the Camarilla, a man with great ambition.
The Holy Vigoor Emperor is the primary antagonist of Ninja Gaiden, Black, and Sigma. Known to the Empire as the Holy Vigoorian Emperor, this is his human form to his God form, the the original Evil Deity who spawned the Fiends.
A secondary antagonist in Modern Warfare 2, Vladimir Makarov takes centre-stage in Modern Warfare 3.
Zant is one of the major antagonists of Zelda: Twilight Princess
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