No Stereotypes Allowed: RPGs that do things differently

I felt like making a list of RPGs that don't just fall in line with being a rip-off of Final Fantasy, Lord of the Rings or Star Wars because I'm a little sick of those. Originality will be rewarded. I'd love to expand the list with suggestions, especially since I've never played one of the Shin Megami Tensei-related games.

If you suggest a game, please also state how and why it's different than the most typical of its genre contemporaries.

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