I finished up DeathSpank in short order and really loved it. But I have a couple issues with it.  

• You have to drag items to the grinder.  It would be nice if there was just a button press for it.
• Once you accept a quest, the info the quest giver imparts is often lost.  Like the location to go to.  So you have to burn hints to get information you've already received.
• It didn't explain how to use inventory objects with the environment.  I knew exactly what I was supposed to do to solve a puzzle, but I had no idea how to make it happen. 
  
• Lock-on loves to focus on objects instead of the enemies attacking you.  Often off the screen so you don't even know you are shooting a chest or a door instead of a baddie.