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A traitor and enemy to the vast majority of Resident Evil's protagonists, Albert Wesker has rapidly achieved super-villain status within the series canon.
A key player in the resistance against the Combine, Alyx Vance accompanies Gordon Freeman throughout much of Half-Life 2 and its related episodes.
Eli Vance is the father of Alyx Vance and the leader of the human Resistance in the Half-Life 2 series.
The Engineer is a character class in the Team Fortress franchise. He is able to build different structures to aid his teammates in the battle.
Gordon Freeman is the iconic main character in Valve Software's Half-Life series, and one of most well-recognized examples of the silent-protagonist.
She worked in a hidden research facility, Black Mesa East with Eli Vance. Appears in a video message in Episode 1 and 2.
Kya, the heroine of the game Kya Dark Lineage.
Lamarr is Dr. Isaac Kleiner's pet headcrab. She appears throughout Half-Life 2 and its episodes.
Master Chief Petty Officer John-117 a.k.a. "the Master Chief" is a SPARTAN-II Commando and is the cybernetically and surgically enhanced super-soldier protagonist of the Halo series.
Shub-Niggurath is the final boss of Quake, the evil threat who was codenamed "Quake" in the story section of the instructions manual. She is invulnerable to normal attacks and can only be defeated by telefragging.
Playable Damage Hero in Overwatch. A brilliant Indian architect who literally bends reality. By manipulating hard-light constructs, she crafts the world as she wishes it to be, in hopes of engineering a perfect society.
Primary antagonist of Half-Life 2 and a general betrayer of humanity.
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