People who have played the fist Uncharted and this one know what I'm talking about.  
 
and keep it spoiler-free. DO NOT EXPLAIN WHAT THEY ARE.

"DO NOT EXPLAIN WHAT THEY ARE." 
Oh..kay. Erhm, those dudes, from the first Uncharted, that I am not allowed to call zombies or spaniards..  

I dunno, I think your title itself might be seen to contain spoilers.
Perhaps you could re-title it as "Which end-game enemies do you prefer, those from Uncharted 1 or 2?"
 
Based on the overall focus of each game, it's kind of easy to see which enemy goes with which game, and then it gets a little into spoiler territory.

" @Abyssfull: Bullet Sponges, yes.. Bolt Sponges, no "

" @ZeForgotten said:

" @Abyssfull: Bullet Sponges, yes.. Bolt Sponges, no "

Yeah, went with old saying of Giving them a taste of their own medicine =P Shame you could never fire the crossbow like an automatic much like they could though O.o "

" @Abyssfull said:

" @ZeForgotten said:

" @Abyssfull: Bullet Sponges, yes.. Bolt Sponges, no "

Yeah, went with old saying of Giving them a taste of their own medicine =P Shame you could never fire the crossbow like an automatic much like they could though O.o "

Well, in their defense they did have a lot of time to practice shooting those things :P "

The game explains exactly what they are, or more accurately Drake discovers it. They are not zombies, they are the cursed sailors who tried to steal the treasure. That's why Drake realizes at the end of the game why they can't keep the statue of El Dorado because whoever takes it will become cursed. 
 
Kind of think of them along the lines as a bunch of golems from Lord of the Rings. Smegal wasn't a zombie; he just devolved into a more primitive creature due to a materialistic obsession, much like the sailors in the first game.

I agree with that. It's definitely a mouth full, but going along those lines you could've also just said cursed sailors =)

"The game explains exactly what they are,  

So the phrase "please no spoilers" gets lost on some people aye? 
 
For me, Scary factor, Uncharted 1, the cause, I was under some Illicit substance, And the creepy factor was up to ten for me. 
 
As enemies, Uncharted 2, because they actually had some tactful manoeuvres. 

Awesome, I have no idea what Guardians or Zombie Spaniards are in this game, but I'm still voting for Zombie Spaniards.
 
Zombie Spaniards, cool band name.

Dude, what the...
Wow.

" @Ujio said:

"The game explains exactly what they are,

 

So the phrase "please no spoilers" gets lost on some people aye?"