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A psychopath in Dead Rising 2.
Demona is a primary antagonist of the Disney animated television series Gargoyles. She has a complicated history with Goliath and a deep hatred of humanity.
Dio Brando is the main antagonist of JoJo's Bizarre Adventure, he manipulates many people behind the scenes in order to eliminate the Joestars and their allies.
Also known as Dr. Cid, he is one of the central antagonists in Final Fantasy XII and is Balthier's father. After going insane in his mad lust for power through the nethecite, he and his ethereal ally Venat stand in the way of Balthier and his allies.
A mad scientist who has battled Wonder Woman on several occasions.
Doctrine Dark is a fighter from the Street Fighter EX series.
Donquixote Doflamingo is one of the 7 Warlords and the ruler of Dressrosa. He is the captain of the Donquixote Pirates and a descendent of the Donquixote Family. He was a former world noble. He possesses the String-String Fruit (Itou-Itou no Mi). He also uses Armament and Conqueror's Haki.
Doomsday is a supervillain who often fights Superman.
An antagonist from Dead Space, Challus Mercer is a crazed scientist on the USG Ishimura and extreme Unitology supporter. He tries to hinder Isaac's progress in returning the Marker.
Main Antagonist of Mega Man Zero 4. he is the former ruler of Neo Arcadia.
A ruthless army sergeant that appears in dead rising 2, he goes crazy after seeing his troops die.
Dylan Fuentes is one of the 'psychopath' boss characters that appears in Dead Rising 3.
Appears to be another happless person trapped within the town with James Sunderland. Eventually turns on James.
Eric Cartman is an animated character from the popular series 'South Park'. Eric Cartman appears in all current South Park games.
Evan is Adam's younger twin brother in Dead Rising 2: Off the Record.
An ancient Sith Lord who's spirit still lingers on Yavin IV
Warmaster of the Chaos Space Marines, previously First Captain, now leader of the Black Legion, successor to Primarch Warmaster Horus Lupercal. He is blessed by Chaos Undivided.
One of Voldemort's most depraved followers, Fenrir Greyback is a notorious Werewolf who is also responsible for Remus Lupin's lycanthropy.
Garfield Lynns lost his job as a movie industry pyrotechnics expert and turned to a life of crime. Utilizing a high-tech suit of his own design, he engages in arson as the super-villain Firefly.
King Bohan's war general. First Boss Nariko faces in Heavenly Sword.
A school bully who tortures Timmy Turner.
Frank Horrigan is one of the leaders of the Enclave and is the final boss of Fallout 2.
Freddy Krueger is a supernatural serial killer. He utilizes his ability to enter people's dreams to kill them. He has been portrayed by Robert Englund and Jackie Earle Haley.
In the Dragon Ball universe, Frieza is a form-changing alien and major conqueror of the known universe.
The second Sub-Zero's arrogant protegé in the Mortal Kombat series, who constantly tries to usurp him as the leader of the Lin Kuei.
Garrosh Hellscream is a character in the Warcraft universe, and is the son of Grom Hellscream, former chieftain of the Warsong Clan.
General Grievous was an antagonist from Star Wars Episode III, and features heavily in all Clone-Wars related Star Wars projects, including videogames. He is a cyborg general for the Separatist army who possesses four arms and the ability to wield Lightsabers.
General Hemlock is the main antagonist in Dead Rising 3.
Ghostface is the antagonist of the Scream movies.
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