Are there any games with significant political/social commentary?

BOMBERMAN HAS YOU BEING THE FUCKING TERRORISTS!!!!

That shit is MAD SUBVERSIVE!!!

I can't think of a better overall social commentary than GTA IV. Not the narrative - but the television, radio, internet and society around you. Marketing, greed, exploitive media, vacuous reality shows... smug liberal talkback and a staunchly conservative Republican senator having a secret gay affair. The celebration of banality, Web 2.0's revolution for stupid people, even club culture is handled well.
 
It's not making a particular statement so much as cynically mirroring modern society - which GTA has always been about, I suppose - but there's a believability to the world in IV that gave that reflection a lot of impact for me. 
 
 Waffling over.

 " Check out some indie games;  http://db.tigsource.com/ 
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• Everyday The Same Dream

" One of the problems with this idea (aside from the fact that most major games are very high-budget, low-risk projects), is that the few games that do attempt to convey deeper messages do so in a way that's largely irrelevant to the actual gameplay. 
Bioshock doesn't actually play like a Randian parable, it plays like System Shock. Metal Gear Solid may be anti-war, pro- "choose life and live" in its themes, but it sure doesn't penalize you much for snapping fifty fuckin' necks.
What will be really interesting is when more designers come up with a way to express the "message" of their games through the rules of the gameplay itself. That's the unique artistic potential that video games represent - the ability to convey a message through rules and consequences. And, to allow you to have an experience of your own, within those rules, at the same time.What's really weird is that Missile Command pretty much did this 30 years ago, and was also a totally awesome game. "

It's like art mimicking life, mimicking art.

A top secret criminal financial organisation has also hijacked the western governments. Some believe their base to be in Tel Aviv, are you Iranian enough to take them down?

*Family guy face*

" @JerichoBlyth:

It's like art mimicking life, mimicking art.

A top secret criminal financial organisation has also hijacked the western governments. Some believe their base to be in Tel Aviv, are you Iranian enough to take them down?

*Family guy face*

"

" @FourWude said:

" @JerichoBlyth:

It's like art mimicking life, mimicking art.

A top secret criminal financial organisation has also hijacked the western governments. Some believe their base to be in Tel Aviv, are you Iranian enough to take them down?

*Family guy face*

"

I see it as a commentary on the Tory/Lib Dem coalition and student riots lol "

Most works have some degree of social/political commentary, as they have to be based on something familiar. 
 
Syndicate Wars (the syndicates and passive violence), Starcraft (the shifts of power and politics), Populous (religions), Half-life 2 (the workings of a dystopian society) , Too Human (the effects of technology on humankind), Left 4 Dead (implicitly), GTA (with loads of social commentary), Mass Effect (universal politics in face of impending doom), Star Wars (the opposing Jedi and Sith philosophies, with many tenants embodies by people in society)... 

" I can't think of a better overall social commentary than GTA IV. Not the narrative - but the television, radio, internet and society around you. Marketing, greed, exploitive media, vacuous reality shows... smug liberal talkback and a staunchly conservative Republican senator having a secret gay affair. The celebration of banality, Web 2.0's revolution for stupid people, even club culture is handled well. It's not making a particular statement so much as cynically mirroring modern society - which GTA has always been about, I suppose - but there's a believability to the world in IV that gave that reflection a lot of impact for me.   Waffling over. "