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Sam McRae is the protagonist of Bad Bots. He is a mechanic on the Titan Hauler, who awakens from his cryosleep to find the crew massacred by robots.
Samus Aran is the protagonist of the Metroid series. As a bounty hunter, she uses her armored power suit to hunt space pirates and other dangerous forces. She frequently crosses paths with dangerous creatures called Metroids in her adventures.
Sandman is a master sergeant in Modern Warfare 3. He leads the Delta Force.
A deuteragonist in the Madness Combat series.
Sankuro is a hammer-wielding criminal who appears in the Samurai Shodown series.
Character from Commandos franchise.
Sarge is the respectable commander and leader of the 911 ELITE team.
Sasha is a Cazar, a cat-like humanoid in the Ratchet and Clank series. Introduced as the daughter of the Galactic President and leader of the military, Sasha eventually becomes mayor of Metropolis, the Galactic capitol.
The main character from Boiling Point.
James "Sawyer" Ford. Character from Lost universe.
Sazh Katzroy, an airship pilot by trade and a father of a young boy, finds himself caught up in a whirlwind series of events that inevitably sets him on his grand journey.
Scarlett (Shanna O'Hara) is a counter intelligence agent on G. I. Joe team. She was the first woman to join the team and is perhaps the best known female Joe. She is romantically attached to Snake-Eyes.
Scott Shelby is one of the four playable characters in Heavy Rain. He is a private detective investigating the case of the Origami Killer.
A dangerous and feared hunter/tracker on the Decepticons team.
A disposable assassin robot of the SCUDCO Heartbreaker variety. He takes fate into his own hands after realizing that he'll self-destruct if his initial mark ever dies.
Adrenaline junkie Seager sought out The Club in order to push himself to the limit. Now he has found them, and wants to play.
Sean Devlin is the main protagonist from The Saboteur. There's nothing he won't do to put the hurt on the Nazis in general and Kurt Dierker in particular. Voiced by Robin Atkin Downes.
Sebastian Malory is a character in The Order: 1886.
A notorious Pirate, always ready for a fight. He is deadly accurate with a rifle, and his trusty ship the Nautilus always comes in handy. He is also the son of the immortal Seth Balmore and despite his age still calls her 'Mommy'.
A mysterious Russian soldier who uses the Sambo syle. He is known as "The White Angel of Death" on the battlefield due to his tremendous fighting ability.
Father of Olga Gurlukovich and leader of a Russian mercenary group who seeks to bring Russia back to power.
Don Morello's younger brother and top earner for the Morello crime family.
Sgt. "Roach" is playable character in Modern Warfare 2. As a member of Task Force 141, he serves under Capt. "Soap" MacTavish.
Jackson is one of the two playable characters in Call of Duty 4. He is a member of the Force Recon squad searching for Al-Asad at the beginning of the game.
Shadow is an artificially created Hedgehog who never ages. He is able to warp time and space with the use of chaos emeralds and is known as "the ultimate life form" in the Sonic universe. He has the same abilities as Sonic the Hedgehog.
Shane Carpenter is the protagonist of the first-person shooter, Haze.
18 year old enigmatic member of Special Execution Agency's (S.E.A.) Phantom Team. One of two playable characters the the game Spy Fiction.
One of the main badguys of "The World Ends With You", and a total math freak.
Chairman of the school board and supervisor of SEES in Persona 3. He has a tendency to make lame jokes, but can be serious when he has to.
A brawny, manly fish with a gun and a cigar.
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