1. Mass Effect 2
Best characters, best story, awesome graphics and art direction, really good gameplay and NO INVENTORY MANAGMENT! Easily my game of the year.
2. Sid Meier's Civilization V
Crack in a game form. What more can you say.
3. Need for Speed: Hot Pursuit
Best looking, best sounding, best playing, most competitive, and the best racing game of the year. With awesome crashes. From the guys that made Burnout. What more can you ask for?
4. Bejeweled 3
5. Sam & Max: The Devil's Playhouse
This is one hell of an game. Incredibly corny, sometimes silly, but mostly extremely funny adventure game. Also it looks the best from all of the Telltale Games... Games, and it features rats and pigeons from German Interns. So wins all around.
6. Greed Corp
Great hex based turn based strategy (not only one on this list), with unique land-destroying feature and nice 50s style soundtrack and visuals. But mostly its a lot of fun online, when you play against other player. Beware, the barrier of enter is pretty high, the game - even offline - is hard. Really hard. But if you get into it, you will find one of the most enjoyable indie games of the year.
7. Fallout: New Vegas
Great RPG. Much, MUCH better than Fallout 3. Where that one was bland, unimaginative, boring and frustrating, NV offers great characters better character progression and main story that you actually give a shit about. But seriously, don't bother with the Xbox 360/PS3 versions the PC is where the game really shines.
8. Mafia II
This well-paced 50s mob story indeared itself to me with great period details, great characters and voice-acting, well done action, and pretty good story. While the lack of optional stuff to do made it not that great of a value, I enjoyed the experience a lot.
9. Kane & Lynch 2: Dog Days
All right, this game is basicly an ok third person shooter. What makes it stand out from the huge faceless crowd of similar games is its incredible art style and well thought-out multiplayer. First: the "bad-mobile-phone-camera-with-shit-smeared-over-its-near-to-no-existent-lens" visual of the game is unbelievable until you see it in motion - the camera man running out-of-synch with the player's character, the lens flares all over the place, the overall "shittines" of the game's graphic make for an unforgettable visual estetique, and the unique multiplayer (well, with dlc map packs at least) made for a fun and also after few patches lag free (at least on PC) experience. You may think that this game has nothing to do on this list, but that is why I made my own. Because I am a bit of an itiot.
10. Amnesia: The Dark Descent
The scariest game of the year. For any fan of horor genre - this is a must play. Sadly, the third quarter of the game got too much puzzle oriented - on't get me wrong, I really like adventure games, sadly this game is build to immerse you in its wonderfully creepy world, and not to make your brain hurt. Also the puzzles were not that hard, and felt just like unnessesary padding. If those parts were just cut, the game would be shorter, but more intense, and in the end better, experience. But this game still packs more punch to the gut than most of big releases over the last five years. So, solid pick for number 10.