Level 10 now, and it's starting to get really creepy, being back on the Ishimura.  it makes me want to go back and play the original.  I've missed a few of the missable achievements, but I am planning on a second run through to max out the weapons etc before a 3rd run through to try to get the Hard difficulty achievement.  I think I'll leave out the hardest difficulty, with its 3 saves, and no checkpoints.....