@-cipher-: I think the most reasonable "connection" to a previous game that we might be able to expect would be her being Sniper Wolf's mother. I have no idea how old Sniper Wolf was, but I think that'd be kinda funny, it being a line of sniper ladies. Aside from that, yeah, she's probably just someone new.
Then again, there is footage of her being "interrogated" in that "red band" E3 trailer from last year, and it's the same room that Huey gets "interrogated" in that trailer. So maybe there is another connection? I dunno.