I just bought Wrath of the Lamb, and am totally hooked on The Binding of Isaac again! If you haven't shelled out the $3 dollars for it yet and are even remotely interested, I highly recommend it. It makes everything way more crazy, even more random, adds tons of new items, environments, and enemies, as well as a host of other features. It also automatically provides the new songs if you have previously bought the soundtrack. For three bucks, or eight if you don't already own the game, I must say it is a very solid purchase.
The New DLC is Fantastic!
This edit will also create new pages on Giant Bomb for:Beware, you are proposing to add brand new pages to the wiki along with your edits. Make sure this is what you intended. This will likely increase the time it takes for your changes to go live.