Best game, or best game ever?
What's great about Picross 3D is that it builds on what made Picross so great. The first Picross made a great game because you got a prize for solving the puzzles. When you solve a sudoku puzzle you are left with a grid with a lot of numbers in random places. It's not very satisfying. When you solve a crossword puzzle you have a jumble of words on a page. Also not every satisfying. Only with the picross games do you get something for your troubles.
That brings us to Picross the James Cameron edition. It's not just that it's in 3D but that the makers of the game have added a hint of ambiguity to the puzzles that makes it more challenging and maybe even a little more satisfying. The only one downfall of this great game is a small nitpick. The 3D figures you make are a little on the silly/abstract side. That's about it.
All in all it's a great game and for 20 dollars you would be a fool not to go out and pick up Picross 3D.