Unless I misunderstood, the latest developer interview seems to flat out state that Shepard dies ("has a permanent story death") at the end of ME2. See for yourself, skip to 1:30 
 

Hrm... strange. Everything i've heard is that he CAN die permanently... but that he doesn't HAVE to die. Basically if you play your cards right you and your team will live at the end. OR you and your team will be DEED!! erm... Dead. Kind of weird to hear this guy just flat out say "He dies."

Yeah, they've been pushing that pretty hard, but do not fear. It's been stated multiple times that one of several outcomes of this "suicide mission" is that Shepard dies during the course of it. That means that that particular Shepard would be dead, and would therefore not be able to transfer into ME3... 'cause he'd be dead, you know. I have to assume you can go back to a prior save (provided you made one), gear up some more and tackle the mission again, but otherwise... yeah, DEAD.

You said that it's the ultimate repercussion or consequence, but it isn't definite. 
Anyways, stuff has been said about this before.

I think it's gonna be a choice. They wouldn't reveal the ending like that. They're probably trying to cook up something more extravagant in save game importing for ME3. Like a choice between Sheppard and a new char. Dunno.

They've said earlier that if you play a certain way your character of shepard "could" die.  It's not written in stone, but if you rush in too quick,  you or members of your party may not make it all the way into mass effect 3.

Bold move on Bioware's part.

I was going to post "WTF SPOILERS DUDE" but then I saw *SPOILERS* in the title.......

But is it truly spoilers when the developers are just giving it away like that?

CRAZY

" But is it truly spoilers when the developers are just giving it away like that? "

Maybe he dies when... You know, you die in the game?
 
Like, it's one of the endings because you died at the final boss fight?

" @Geno:   They've already stated that there are multiple endings and that all the teammates including Sheparrd are completely expendable in this sequel. "

They stated this a long as time ago though dude. They said if you make the right decisions, you won't die in the end, but its entirely possibly for you to die outright, I guess you actually wouldn't be able to do that save in the next game then and would have to redo it.

It has been confirmed by Casey Hudson on the ME official forums that if you die at the end of ME2, you can't load your save in ME3, and ME3 starts with a default backstory where Shepard survives.
 
Basically, it's only a "permanent character  death" if you don't play ME3. It's barely better than a normal game over.

Tali is a lot more grown up. Okay. More importantly you can have romances with characters from the first game that you could not before. So he's pretty much telling us outright that you can engage a tactical insertion into Tali's disgusting alien vagina. Awesome!

Or some Wrex bareback.

I think everybody and their mother knows that.
But what I kinda hate about these vids is the ammount of info they are giving away.
Safe to say I won't have a 'pure experience'

" I think everybody and their mother knows that. But what I kinda hate about these vids is the ammount of info they are giving away. Safe to say I won't have a 'pure experience' "