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The scantily-clad main character in Code of Princess. Her father has given her a holy sword and asked her to stop the monsters attacking the royal castle.
The Sole Survivor is the protagonist of Fallout 4.
Soleil is one of supporting characters in Fire Emblem Fates.
Solid Snake is the main protagonist in a number of the Metal Gear games. An expert in infiltration and espionage, Snake has completed countless missions and is repeatedly tasked with disarming the latest incarnation of Metal Gear. He is voiced by David Hayter in the English versions, Akio Ohtsuka in Japanese.
The third 'Son of Big Boss', created as part of the Les Enfants Terribles project along with Liquid and Solid Snake.
Soma Cruz is the protagonist of Castlevania: Aria of Sorrow and the sequel, Dawn of Sorrow. He is capable of absorbing the souls of demons, thereby acquiring their powers.
The female protagonist of Rune Factory: Tides of Destiny. Being sweet, cheerful, and a bit childish, her spirit is rarely dampened, even in the worst situations.
One of the Six Great Generals, taking the position after her mother died. Fiercely loyal to Tir's father Teo, might be something going there.
Soonog is the guildmaster of the Greenblood Knights, which is the shadow knight guild in Oggok.
Sophia Dryden was a Grey Warden Commander that met her end at Soldier's Peak.
Greek warrior, one of the main characters in the SoulCalibur Series, Sophitia received an oracle to destroy Soul Edge from Hephaestus, the god of fire and smithery. The thrust attacks from her sword as well as shield attacks are extremely powerful. Cassandra is her sister.
The lead character for Tales of Zestiria.
The living incarnation of Soul Edge's pure, malevolent will. Known as Soul Edge or Inferno, it is the source of corruption that transformed Siegfried into Nightmare.
The main protagonist of the Rocket Knight Adventure Series. Sparkster is armed with a sword that can project energy over a short distance and a rocket pack that allows him to fly.
Specter Knight is a character from Shovel Knight.
Sphinx, a demi-god, is the main protagonist in Sphinx and the Cursed Mummy.
Spinal is a reanimated skeletal warrior created by Ultratech as an experiment in cellular regeneration. His trademarks include teleportation, shapeshifting, and a really creepy laugh.
Spiral is a henchman for Mojo. She has teleportation powers, and six arms.
Squall is the main character from Final Fantasy VIII. He wields a gunblade and has a lone wolf attitude, disliking the presence of other people, though his emotional distance and gruff exterior hides the heart of a thoughtful, deeply caring young man.
Sragg Bloodheart is the guildmaster of the shadow knights in the Bloodsabers, which is a guild that meets secretly in Qeynos Catacombs at the Temple of Bertoxxulous.
The king of reincarnated skeletons. He's pretty huge.
A master swordsman of Beorc and Laguz heritage. He dwells in the Grann desert, found in Begnion.
The older sister of Loretta, and daughter of Eric Lecarde. In Portrait of Ruin the evil Brauner turns Stella and her sister into vampires that are under his control.
A main character in Final Fantasy XV. She is described as an "unfortunate" enemy of the protagonist Noctis.
The default male character and protagonist in Minecraft and also makes an appearance in the PC version of Super Meat Boy as an unlockable character!
Stocke is the protagonist of the Atlus RPG Radiant Historia. He works as a spy for the nation of Alistel.
The main character of Strider Returns.
A Ninja of the future. Hiryu fights to stop evil and corruption all over the world.
The tiny god of medicine in Shinto mythology.
A king from an earlier age who was corrupted by Sauron and turned into one of his Nazgul
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