This is just about the most perfect game for this. Its hard on the eyes and ears to play it like that for ten plus hours, but it makes the experience so much better. Will you or won't you?

I will. Did it with Dead Space 1 and it was scary as hell.

I just can't do it. Unless I want to progress at a snail's pace, I can't play it without some lights on.
 
Headphones though, yes.

Will play it in the dark, but not with headphones. I have a nice surround reciever/speaker set, so that would surely trumpf any headset I currently own. Will be turning the volume up though :-D

During the daytime while there is at least 1 more person in the house. 
 
I do not enjoy scary stuff, it doesn't give me a rush. I will play the game for the gameplay and story (really digging the unitology stuff).

I'm playing the first Dead Space in a dark room (have to with a projector) and surround sound, and I'll be doing the same with this! Dead Space has some of the best sound design I've ever heard, and the surround sound makes thing extra unnerving. I really hate those doors that open and close really fast.  :(

Either years of horror movies watching callused my psyche or that I am just not that easily scared. I don't know how people found Dead Space scary. Don't get me wrong, good game, but not at all scary. It more relies on startling you then actually getting you scared.  
 
@SSValis: It's way better to play it with a surround sound system. 

I will watch my housemate play it through my fingers... god I'm a pussy.

Probably, yes. 

only way to play!!!!!! right now playing through dead space mobile for the phone/touch/pad on my touch 4 looks awsome in retina, this game is incredible on here and if you have a device you owe your self to play it, plus its only 6.99 and story takes place right before dead space 2 begins, you also get a special item and a power node for the console/pc version if you register it.
 
MY GOD I JUMPED OUTTA MY CHAIR LOL! earphones FTW! sound is awsome as hell on mobile version too! its dead space for your iphone you cant go wrong.

No but the room will be dark and the screen shall be 55' complimented with 5.1 surround sound.

" Either years of horror movies watching callused my psyche or that I am just not that easily scared. I don't know how people found Dead Space scary. Don't get me wrong, good game, but not at all scary. It more relies on startling you then actually getting you scared.  
 
@SSValis: It's way better to play it with a surround sound system.  "

I'll play late at night in the dark, but I don't have headphones or surround sound. Makes me sad. 

Dark room, yes. Headphones, probably not.

Nope. Bright room, regular-ass speakers. I'm also thinking about listening to Life is Beautiful whilst playing it. Well, maybe not that last part. 

Don't have headphones. 

already did.  pretty much a horror game custom for me now. 

" I will. Did it with Dead Space 1 and it was scary as hell. "

Currently playing in a dimly lit room with my Astro A40s. The sound is what scares me the most. Definitely a must with Dead Space.

I cant play with all the lights off,  my 50 inch gives me a headache after a while, so I am using a lamp with nice 5.1 surround setup.

FUCK NO. I'll have headphones on since they are the only speakers hooked up to my PC that are worth a damn, but I'll be playing it with the lights on during the day. I get freaked out by video games pretty easily. Movies, on the other hand, have no such effect. In a movie I can go, "Don't go down that hallway. That's a terrible idea." With a video game, it's, "Oh shit, I have to walk down this hallway." For some reason it makes a huge difference for me.

Using my wireless WoW headphones on my computer in a room with dark curtain.
Already had some jump scares, that game has some awesome surround.

Hearing something running up behind me just to turn around and be knocked off my feet by some awful fast running alien thingy is scary as hell.

Dark room, yes. Headphones, god no. Surround sound!

I play everything with headphones.

Of course i will...if i want to get insomnia -.-

I remember playing the first game this way while taking care of a friend's cats. The biggest scare I got was one of the cats jumping onto the back of my chair during a really intense part in the game. I think I almost had a heart attack.

Dark room, yeah. I don't have a good pair of headphones, though. I should look into that.

I didn't have my headphones for the first one, but I do now, and I've already jumped way worse than the first one! 
 
This game is so awesome!

Head phones are a must for any game that you want to scare you.  I know this might be completely backwards to some gamers, some seem to actual not be able to handle the tension in Dead Space.  But for us, the people who enjoy being scared, it is a must.  I actually bought a pair of Astro A40 headset and wireless Mix Amp, and it is perfect for gaming.  I often times have to take the headset off to make sure that the sound is not actually coming out of the TV and super loud.  Then just turn off all the lights and sit 4 feet away from your HD TV and get ready get the piss scared out of you.  The sound in Dead Space 2 is probably the best part, and anyway to amplify the experience is well worth it.

 I spend most of my time in the dark with headphones on...

Yes. it's not about being scared for me, but just for the experience. When I'm playing a game that has a very dark environment and a lot of atmosphere I like to play at night with headphones on. It's about getting rid of as many external stimuli as possible so that I can really get lost in the game.

It is the only way I will play it. I refuse to play during the day time. It is so much better this way, though i do jump more and sometimes make a fool of myself, it so worth it. 

Surround Sound with sub woofer will always be > any headset. Means it isn't uncomfortable, and having the walls shake cause it's so loud is always a more satisfying experience. 
 
This coming from someone with a surround sound headset for PC gaming, and SS system for my console.

HELL NO! 
 
Way too big of a chicken for that. If there were a "remove all jump scares" option, I'd use it in a heartbeat.

Currently doing just that.

fuck no