You can only keep 1 game in your life, what would it be?

Like most people in this thread, my answer is DOTA 2. There is enough game there to last me a lifetime; if it wasn't for my cultural curiousity, I don't think I'd even bother playing other video games.

Stronghold Crusader, best RTS of all time imo.

Sonic's Ultimate Genesis Collection.

rFactor 2

I need mah racin' and it has a bunch of stuff available with great physics. It already looks dated, so I wouldn't regret my decision later. ;P

Dwarf Fortress.

I've never actually played it, but i've heard it's crazy deep and takes forever to learn.

Weirdly enough, Lumines comes to mind for me.

the World Of Warcraft.

Fallout 2, they should have just let the franchise end there.

Civilization.

Game Genie

Probably Skyrim. I've put about 500 hours into that game across the 360 and PC and I still find something new every time I play.

My head titled a fraction the left and I mouthed a silent "Wha...?"

Assuming I have access to all expansions and such, World of Warcraft would be my choice. I could play that game forever, as long as I had some friends to play it with.

Definitely Counter-Strike, and, assuming other people stuck on that version with me, then I'd probably take CS GO. I've put thousands of hours into the series already and haven't gotten bored, so I feel pretty safe assuming I won't soon.

Paper Mario (N64)

I don't what it is about that game, but it's the only one I've gone back and played to completion over a dozen times; and still want to play it more.

Since it's release, Skate 2 has gotten the most play from me to date, I think. The soundtrack could be my life soundtrack, the environment you're thrown into I'd be happy to live in, you have the wonderful Reda keeping you company, and all you ever have to really worry about is skating. There are missions to do if you want, but if you just want to skate, find any old spot to skate or make a spot yourself, you can.

I feel like MOBAs have the depth to keep people going forever, I just have to learn how to play one of them :P

If I can play all the permutations, mods and multiplayer, probably ARMA 3

If I could have access to multiplayer and mods, Minecraft. If not, Elder Scrolls III: Morrowind

Ultra Street Fighter 4.

Super Meat Boy.

This depends. I'd say World of Warcraft but if this applies to everyone in the world then I'd depend on a whole bunch of other people also choosing World of Warcraft as their one game to play, so in that situation I'd probably be safe and pick either Dark Souls 2 or Castlevania: Symphony of the Night.

Actually I change my mind: Civilization V w/ all the DLC

I already only have one game in my life. It's Dota 2, and I regret nothing.

For me definitely Dota 2. I get endless entertainment from it

That's pretty funny. I suppose that would be a common reaction. I based the decision on having a game that I can spend one minute or hours in and have the same amount of enjoyment. A game that every time I go back to, it ends up still being fun and takes up a lot of my time. An open world experience with no shortage of dumb and fun stuff to do. Graphics aside, Saints Row 2 is the best in the series IMO, and fits those requirements for me.

Dota 2

Persona 4 or Rock Band.....3. I would argue 2 is the better game but 3 has all the songs.

Binding of Isaac. Pretty much play it daily anyway.

fifa 12

DotA2. I wouldn't call it my favorite game of all time, but considering the 2000 fucking hours I've dumped into it, I'd say there's plenty of replayability there.

Football Manager

I'm glad I'll never be in this situtation again, but I'd have to go with WoW because it was the only game I played for 6 years and I enjoyed it completely, It's constantly evolving and there is always something to do. Anything else I'm sure I'd get very bored of and just stop playing video games altogether.

World of Warcraft here as well. Even with it's current community it'd still be something I could sink months and months into.

Probably an MMO that will see updates for as long as I live. Second option would probably be something competitive like Dota2. Lots of game modes and always people around to play.

Ultimate Marvel vs. Capcom 3, because if it was the only game I could devote time to at all, I could probably get professional at it. That, and the character roster would serve as a stark reminder of all the games that I'll never be able to play again. I'll see Arthur and get depressed that I can't even look at Ghouls'n Ghosts for the Genesis as long I'm alive. That's fun.

Final Fantasy XIV probably

Dwarf Fortress, final release. It will be the most incredible thing of all time - a true work of art.

But then again, that would be more like an alternate reality than a mere game, so I don't know if it would even count.

@radleyduder: I should have got skate 2 last week on 360. Every time it comes up 3.74 I turn it down.

Tetris

One game is hard but if i have too choose, path of exile. Infinite builds to try out and with the expansions this game will still be relevant in time.

tetris

Dark Souls

all these responses sounded bad to me until I saw someone post Civ

so yeah, probably civ 4 or 5 for me

Even though I don't play it anymore, I would say World of Warcraft. For me, leveling to max level with every character and maybe every race. End game stuff. I could definitely keep busy with that game for years to come.

If I had access to great internet or people to play with, USFIV

Morrowind.

If I have internet to play with other people, it has to be Dota 2.

If I am isolated? Dwarf Fortress.

If I don't get the internet/people to play with, then... Minecraft? Something like Minecraft?

Honestly plenty of competitive options would work if multiplayer is an option. Quake, Street Fighter, even something like Hearthstone.

xcom: enemy unknown, or FTL

A properly modded Skyrim is a thing of beauty; ever evolving, constantly changing. I currently have 522 hours into Skyrim (PC) and I am certain I could do another 500 without effort.