Announced at E3 2018 at Microsoft's Press Conference, Devil May Cry 5 is a return to the original Devil May Cry series which last had a full instalment in 2008 with Devil May Cry 4.
The game's story is set following the 3rd, 1st and 4th game and the position in the timeline in relation to the second title is currently unclear. There is an invasion of demons in Red Grave City following the spawning of a demon tree there and Nero returns as a playable character from the fourth game with his iconic Devil Bringer arm being replaced by a bionic Devil Breaker following a bloody encounter with a mysterious foe.
Nero now runs as a separate branch of Devil May Cry, a demon-hunting business while Dante, his superior is also seen in the initial trailer for the game on a motorcycle and expected to be along with Nero as two of the three confirmed playable characters.
The third character is assumed to be another mysterious figure featured on the cover art.
This game marks the return of Hideaki Itsuno as the director, who also led Devil May Cry 2, Devil May Cry 3 and 4 along with their upgraded versions.
The game has been confirmed to be running on the Capcom's RE Engine as the 2019 Resident Evil 2 remake and 2017's Resident Evil 7 rather than Capcom's MT Framework which was used for DMC4, Dragon's Dogma (also directed by Itsuno) and 2018's Monster Hunter: World. This came with a focus on photo-realism but the game aims to maintain the smooth 60 frames-per-second that the series is known for.