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Sabretooth is the primary enemy of Wolverine. He has adamantium laced claws, a healing factor, and enhanced strength.Sabretooth was created by Chris Claremont and he first appeared in Iron Fist #14.Sabretooth's real name is Victor Creed.
Sander Cohen is the insane artist who runs Fort Frolic in the game Bioshock. In the game he asks the player to photograph dead bodies so that he can display the photos as part of his "masterpiece".
Satan is the Devil, the incarnation of Evil in the universe, the Lord of Hell, the Prince of Darkness, and a very prominent figure in the Abrahamic religions. Naturally, he appears in many videogames, often as a final boss or last encounter. He is commonly depicted as a tempter that leads the faithful astray, and it's generally a bad idea to trust him.
Scarecrow is an antagonist in the Batman universe who specializes in inducing fear in his victims.
Another violently unstable dinosaur hybrid created by the good people at InGen
Screaming Mantis is the final member of Beauty & the Beast Corps. that you will encounter in Metal Gear Solid 4 and is the leader of the unit.
Sebulba was the reigning champion of the Outer Rim Podrace circuit in the waning days of the Republic. Sebulba flies dirty, and will even stoop to sabotaging a competitor's Podracer before the race begins.
Character from Commandos franchise.
Sektor is a red cyborg from the Mortal Kombat franchise. Sektor was the son to the Grandmaster of the Lin-Kuei.
A corrupt security guard who goes on a power trip amidst the zombie outbreak in Fortune City. He is a psycho you can encounter in dead rising 2.
Possessing immense strength and boundless knowledge of the dark arts, Shao Kahn rules Outworld with merciless brutality. He desires nothing less than the total subjugation of all realms, so that they may be united under his own dominion.
Shinnok is an Elder God of immeasurable power and ruler of the Netherealm.
Shredder is the archenemy and main villain in most of the Teenage Mutant Ninja Turtles franchise.
Sideshow Bob, or uncommonly known as Robert Underdunk Terwiliger, is a criminal 'mastermind' in The Simpsons who is constantly foiled by Bart Simpson. He is voiced by Kelsey Grammer.
Slaanesh's greatest and most favored mortal champion, the outwardly handsome but inwardly hideous Sigvald is a fierce warrior and fiercer narcissist. Once made war on the Elves simply because he heard tell that their hair was nicer than his.
One of the fiercest of all of Khorne's Bloodthirsters, Skarbrand is filled with unending hatred and lust for slaughter, all while futilely hoping his master will one day forgive him.
One of the most deviously intelligent and resourceful Goblins to ever live, Skarsnik leads the Crooked Moon Tribe, and is regularly battling the Dwarfs led by Belegar Ironhammer for control of Karak Eight Peaks. Often accompanied by a Squig when going into battle.
Psychopath boss character from Dead Rising 2
A psychopath from the original Dead Rising and Dead Rising: Chop 'Till you Drop. He doesn't allow vandalism in his store.
Superwoman is the evil amalgamation of Lois Lane and Wonder Woman from a parallel Earth.
This homicidal harlequin has been the face of Playstation's Twisted Metal game series from Day 1.
Syndrome is an enemy of the Incredibles.
Caulder's oldest daughter from Advance Wars: Days of Ruin. Believes she's clearly superior than everyone else and thinks nothing of crushing people beneath her feet.
Also known as "General Tao" in the US.
One of Khorne's mightiest mortal champions, Taurox is an exceptionally vicious and bloodthirsty Minotaur whose bronze hide makes him all but invulnerable.
His real name is "Not important" and he is the main character of Hatred.
A nightmarish fusion of Batman and the Joker, the Batman who Laughs is the leader of the Dark Knights and in many ways the most dangerous of them all. Certainly, he is the most evil.
The Beast is a savage raider from Advance Wars: Days of Ruin. He relishes in a kill-or-be-killed world where he can satisfy his bloodthirsty nature.
The main character of the Saints Row series and, as of Saints Row 2, the leader of the 3rd Street Saints.
The Comedian, secretly Edward Morgan Blake, is one of the original Minutemen from Watchmen, and his murder is the catalyst for the events of the graphic novel.
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