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The BFG 9000 is a famous gun in the Doom series, and the most powerful gun in the game. The BFG, or Big Fucking Gun, shoots a ball of plasma that detonates on contact with a solid object. It can also be charged for greater damage and larger blast radius, but if charged for too long, it will detonate and kill the player. Many games have had guns inspired by the BFG 9000, and Quake II even featured a more advanced model, the BFG 10,000.
In the Doom Bible - the game's original design and concept document, written by Tom Hall - a weapon referred to as "BFG 2704 (red)" is described as "Horrible hallway-scouring weapon. Damages user a bit. Awful recoil. BFG stands for "Big Fucking Gun." Safest use: back to wall, distant target."
The BFG 9000 is a one shot kill for all enemies, even in ultra-violence mode, except Cyberdemons (3 shots) and Spider Masterminds (2 shots).
In the movie Doom, it is designated the "Bio-Force Gun". In a nod to popular interpretation of the BFG acronym, after firing the weapon at an unseen creature, Sarge exclaims, in surprise, "Big...fucking gun."
Hank Leukart 's "Official" Doom FAQ (1994) claims the F to stand for Fraggin': "Being the most powerful weapon, the only thing BFG9000 could stand for would be "Big Fraggin' Gun." :) "