TrafalgarLaw

It depends on an individual basis, some people have almost zero problems after the transplant. The most comfortable transplants are those in which your own stem cells (gained through the umbilical cord or via blood) are used, a bit modified and injected back into your blood. Miraculously, they always find their way to the bone marrow and start life anew. You don't even need immunosuppresive medication if it's your own stem cells.

The transplant itself isn't that taxing, the prerequisite steps taken and maintenance of the transplant can be.

I like the picture, it's a nice way of saying Ryan will always be with them, and always in our hearts.

It isn't a cure by any means. Lets hypothetically say you eradicated all immune cells infected by the HIV virus by performing bone marrow transplant. There are a lot of (hidden) reservoirs the HIV virus can reside in, giving you a relapse into aids.

The bone marrow transplant procedure has a high mortality of around 20-25%, higher in children. Though we now have a much safer way of transplanting through injecting G-CSF mobilized stem cells directly into your bloodstream, instead of sticking a thick (aspiration) needle into your bone (marrow). Depending on which one the doctor goes for is important.

A lot of immunosuppressive medication is used just to keep the transplant in check (auto-immune graft vs. host disease). These are drugs with terrible side effects like causing diabetes, weight gain, opportunistic infections that can even lead to cancers (lymfomas, kaposki sarcoma), mood swings etc.

Europe is a tier 3 "country" now?

Is this an attempt to insult people from the UK "being stupid enough to buy Knack"? For all it's worth, at least Knack works and didn't need a formal apology from the developers and publisher.

I wish I woke up 30 mins ago, sent a PM to mods. Don't do it, you have us.

You're saying immigrants, i.e. Polish people (usually white men) immigrating into european countries cannot face discrimination or hardships? Or white men with obesity? Or maybe a cleft lip? C'mon man, saying that white people cannot be discriminated against is a misconception. Yes, it happens a lot less but that doesn't mean white people have this magical thing called "privileges" or cannot empathize with those have been discriminated against.

I at least applaud OP saying she can fend for herself, though I'm not sure everyone else can.

I wouldn't worry too much, Xbox's days are numbered. Recent UK charts show that Knack (I puppy you not) outsold FM5, BF4 and all XB1 titles alltogether. Indies are going to make or break consoles this generation and Microsoft is showing their contempt at them. For now, boycotting XB1 would help their dev cycles instead of sitting on finished games while they try to even get it working on XB1.

I'm sorry but no, I cannot accept this and won't stand for it.

A shark (squalus acanthias), a squid (loligo vulgaris), a starfish (asterias rubens), a worm (lubricus terrestis), a jellyfish (scyphozoa scyphomedae), a sheep heart, cow lungs and a real human (homo sapiens).